The paper examines the relationship between the consul Lucius Cornelius Sulla and the Roman plebs in 88 B.C.The first part of the paper considers the role of the popular assemblies in the political struggle around the bills of the plebeian tribune Publius Sulpicius.The authors take the view that the violent clashes between supporters
PolySialic Acid Nanoparticles Actuate Complement-Factor-H-Mediated Inhibition of the Alternative Complement Pathway: A Safer Potential Therapy for Age-Related Macular Degeneration
The alternative pathway of the complement system is implicated in the etiology of age-related macular degeneration (AMD).Complement depletion with pegcetacoplan and avacincaptad pegol are FDA-approved treatments for geographic atrophy in AMD that, while effective, have clinically observed risks of choroidal neovascular (CNV) conversion, Board optic
Silicon modifies leaf nutriome and improves growth of oak seedlings exposed to phosphorus deficiency and Phytophthora plurivora infection
Beneficial effects of silicon Pinger Carver (Si) on plants have primarily been studied in crop species under single stress.Moreover, nutrient acquisition-based responses to combination of biotic and abiotic stresses (a common situation in natural habitats) have rarely been reported, in particular in conjunction with soil amendments with Si.Peduncul
Biosynthesis of the Textile Dye Indigo by a Recombinant Bacterium
The biosynthesis of indigo by microorganisms can be manipulated through molecular biological techniques that alter the stability, activity, and final product of biosynthetic pathways in the cell.Transformed microorganisms may synthesize indigo at commercially significant rates and yields from glucose and other simple precursors.A cluster of five ge
Progressive familial intrahepatic cholestasis type 4: a case report
Abstract Background Progressive familial intrahepatic cholestasis is an autosomal recessive genetic disorder that manifests primarily with jaundice and pruritus and can progresses from persistent cholestasis to cirrhosis and late childhood liver failure.Classically, progressive familial intrahepatic cholestasis is classified into three subtypes: 1,